Mathematical Algorithms – selected publications
Physiological time-series analysis using approximate entropy and sample entropy.
Am J Physiol Heart Circ Physiol. 2000 Jun;278(6):H2039-49.
Sample entropy analysis of neonatal heart rate variability.
Am J Physiol Regul Integr Comp Physiol. 2002 Sep;283(3):R789-97.
Accurate estimation of entropy in very short physiological time series: the problem of atrial fibrillation detection in implanted ventricular devices.
Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H319-25.
Breath-by-breath analysis of cardiorespiratory interaction for quantifying developmental maturity in premature infants.
J Appl Physiol. 2012 Mar;112(5):859-67.
Dynamic analysis of cardiac rhythms for discriminating atrial fibrillation from lethal ventricular arrhythmias.
Circ Arrhythm Electrophysiol. 2013 Jun;6(3):555-61.
Local dynamics of heart rate: detection and prognostic implications.
Physiol Meas. 2014 Oct;35(10):1929-42.
Predictive Analytics Monitoring – selected publications
Predictive monitoring for respiratory decompensation leading to urgent unplanned intubation in the neonatal intensive care unit.
Pediatr Res. 2013 Jan;73(1):104-10.
Predicting the need for urgent intubation in a surgical/trauma intensive care unit.
Surgery. 2013 Nov;154(5):1110-6.
Signatures of Subacute Potentially Catastrophic Illness in the ICU: Model Development and Validation.
Crit Care Med. 2016 Sep;44(9):1639-48.
External validation in an intermediate unit of a respiratory decompensation model trained in an intensive care unit.
Surgery. 2017 Mar;161(3):760-770.
New-Onset Atrial Fibrillation in the Critically Ill.
Crit Care Med. 2017 May;45(5):790-797.
Cardiorespiratory dynamics measured from continuous ECG monitoring improves detection of deterioration in acute care patients: A retrospective cohort study.
PLoS One. 2017 Aug 3;12(8):e0181448.
Identifying the low risk patient in surgical intensive and intermediate care units using continuous monitoring.
Surgery. 2018 Apr;163(4):811-818.
Dynamic data monitoring improves predictive analytics for failed extubation in the ICU.
Physiol Meas. 2018 Jul 16;39(7):075005.
Clinical Implementation and Impact – selected publications
Mortality reduction by heart rate characteristic monitoring in very low birth weight neonates: a randomized trial.
J Pediatr. 2011 Dec;159(6):900-6.e1.
Computers in White Coats: How to Devise Useful Clinical Decision Support Software.
Crit Care Med. 2016 Jul;44(7):1449-50.
Impact of predictive analytics based on continuous cardiorespiratory monitoring in a surgical and trauma intensive care unit.
J Clin Monit Comput. 2018 Aug 18.
Advancing Continuous Predictive Analytics Monitoring: Moving from Implementation to Clinical Action in a Learning Health System.
Crit Care Nurs Clin North Am. 2018 Jun;30(2):273-287.